JINSAI SHANG, Ph.D.
2021-Present: Guangzhou Laboratory, Professor (广州实验室, 研究员)
2020-2021: GRMH-GDL, PI (生物岛实验室神经代谢与再生研究中心, 研究员)
2015-2020: The Scripps Research Institute, Postdoc (斯克利普斯研究所, 博士后)
2010-2015: SIU-Carbondale, Ph.D. (南伊利诺伊大学, 化学, 博士)
2006-2010: Wuhan University, B.S. (武汉大学, 理学学士, 化学基地班)
Jinsai Shang received his B.S. degree in Chemistry from Wuhan University and his Ph.D. degree from Southern Illinois University Carbondale, where he was trained in biophysics and structural biology using X-ray crystallography and NMR spectroscopy. In 2015, he joined the laboratory of Douglas Kojetin at Scripps Research as a postdoctoral fellow, where he investigated the molecular and structural mechanisms by which synthetic and endogenous ligands regulate nuclear receptors, including PPARγ, with an emphasis on ligand-induced receptor activation, repression, and structure-guided drug discovery. In 2020, Dr. Shang joined the Center for Neuro-Metabolism and Regeneration Research at Guangzhou Regenerative Medicine and Health Guangdong Laboratory (GRMH-GDL) as a principal investigator, and his laboratory moved to Guangzhou Laboratory (GZL) in 2021. His current research focuses on drug discovery for respiratory diseases, including respiratory viral infections, lung cancer, and chronic respiratory diseases, with particular interests in structural pharmacology, medicinal chemistry, high-throughput drug screening, and new methods for drug target identification and mechanism-of-action studies.
E-mail: shang_jinsai@gzlab.ac.cn